Asamoto A, Yablonski M E, Matsushita M
Department of Ophthalmology, University of Nebraska Medical Center, Omaha, NE, USA.
Ophthalmic Surg Lasers. 1996 May;27(5):355-60.
The authors retrospectively examined the potential for early postoperative intraocular pressure to predict the long-term results of initial trabeculectomies.
The records of 173 patients (207 consecutive eyes) who underwent initial trabeculectomies, which were performed by one of the authors between 1983 and 1991, with a minimum follow-up of 150 days were reviewed. Cases of trabeculectomy combined with cataract extraction were excluded.
The intraocular pressure during postoperative week 1 was the same for patients with successful initial trabeculectomies (success group) as it was for patients with unsuccessful trabeculectomies (failure group). However, the intraocular pressure during the second, third, and fourth weeks was significantly higher in the failure group (P < .001). Laser suture lysis and 5-fluorouracil had no influence on the fact that high intraocular pressure during the first postoperative week had no prognostic significance.
Positive results on postoperative Seidel tests did not predict a poor prognosis. However, high intraocular pressure after the first week may require intervention because it predicts a poor prognosis.
作者回顾性研究了术后早期眼压预测初次小梁切除术长期效果的可能性。
回顾了1983年至1991年间由其中一位作者实施的173例患者（207只连续眼睛）初次小梁切除术的记录，这些患者的最短随访时间为150天。排除了小梁切除术联合白内障摘除术的病例。
初次小梁切除术成功的患者（成功组）术后第1周的眼压与小梁切除术失败的患者（失败组）相同。然而，失败组术后第2、3和4周的眼压明显更高（P <.001）。激光缝线松解术和5-氟尿嘧啶对术后第1周高眼压无预后意义这一事实没有影响。
术后Seidel试验阳性结果并不能预测预后不良。然而，术后第1周后眼压升高可能需要干预，因为它预示着预后不良。
