Renaud R, Dervain I
J Gynecol Obstet Biol Reprod (Paris). 1977 Mar;6(2):169-92.
The authors, who practised for years in Africa, present the present view on the effects haemoglobinopathies have on pregnancy and on modern therapeutic methods. They point out that among these haemoglobinopathies by far the most serious is haemoglobin SS or heterozygote S associated with haemoglobin C or with betathalassaemia. On the other hand, pregnancies in patients with the sickle-cell trait (HbSA) are often very well tolerated.