吡啶衍生物与细胞色素P - 450的结合
Binding of pyridine derivatives to cytochrome P-450.
作者信息
Born J L, Vaughn D
出版信息
J Pharm Sci. 1977 Jul;66(7):1046-7. doi: 10.1002/jps.2600660739.
PMID:886443
Abstract
The spectral binding constants, Ks, of pyridine, methylpyridine, and dimethylpyridines were determined. The Ks values of the compounds were discussed in terms of mechanisms of possible bonding to cytochrome P-450.
摘要
测定了吡啶、甲基吡啶和二甲基吡啶的光谱结合常数Ks。根据这些化合物与细胞色素P - 450可能的结合机制对Ks值进行了讨论。
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