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小脑星形细胞瘤:13例20岁以上患者的报告及文献复习

Cerebellar astrocytoma: report of 13 cases aged over 20 years and review of the literature.

作者信息

Hassounah M, Siqueira E B, Haider A, Gray A

机构信息

Department of Neurosciences, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

出版信息

Br J Neurosurg. 1996 Aug;10(4):365-71. doi: 10.1080/02688699647285.

Abstract

Cerebellar astrocytoma in adulthood is a distinct neoplasm with a variable prognosis. We reviewed retrospectively 13 cases in patients aged 21 years or over, seen between 1976 and 1992. These accounted for 19% of all cases of cerebellar astrocytoma seen during that period. The tumour was located in the midline in six patients and laterally in seven; seven patients were females and six were males. The low grade tumours had an overall favourable course, similar to that seen in cerebellar astrocytoma in childhood, with follow-up ranging from 4 to 10 years. The poorly differentiated form, seen in four of the cases, showed progression or recurrence within 4-24 months, regardless of the extent of removal or post-operative radiation therapy.

摘要

成人小脑星形细胞瘤是一种具有不同预后的独特肿瘤。我们回顾性分析了1976年至1992年间所见的13例年龄在21岁及以上的患者。这些病例占该时期所见小脑星形细胞瘤所有病例的19%。肿瘤位于中线的有6例,位于侧方的有7例;女性7例,男性6例。低级别肿瘤总体病程良好,与儿童小脑星形细胞瘤相似,随访时间为4至10年。在4例病例中所见的低分化形式,无论切除范围或术后放疗情况如何,均在4至24个月内出现进展或复发。

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