糖尿病心脏中的线粒体DNA突变
Mitochondrial DNA mutations in diabetic heart.
作者信息
Takeda N
机构信息
Department of Internal Medicine, Aoto Hospital, Jikei University, School of Medicine, Tokyo, Japan.
出版信息
Diabetes Res Clin Pract. 1996 Jul;31 Suppl:S123-6. doi: 10.1016/0168-8227(96)01239-9.
PMID:8864650
Abstract
Mutations of mitochondrial DNA have been found in cardiomyopathic and diabetic patients as well as mitochondrial myopathic patients. Mitochondrial DNA mutations are maternally transmitted. It has also been reported that these mutations can be acquired under the influence of free radicals. This article is a mini-review about mutations of mitochondrial DNA related to the diabetic heart.
摘要
线粒体DNA突变已在心肌病患者、糖尿病患者以及线粒体肌病患者中被发现。线粒体DNA突变通过母系遗传。也有报道称，这些突变可能在自由基的影响下获得。本文是一篇关于与糖尿病性心脏相关的线粒体DNA突变的小型综述。
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