Dodsworth N, Harris R, Denton K, Woodrow J, Wood P C, Quirk A
Delta Biotechnology Limited, Nottingham, U.K.
Biotechnol Appl Biochem. 1996 Oct;24(2):171-6.
Recombinant human albumin produced in the yeast Saccharomyces cerevisial and human serum albumin derived from blood fractionation were compared by a series of analytical techniques. These demonstrated that the two proteins were equivalent structurally. However, differences observed in some of the assays indicated that the recombinant product had lower levels of structural heterogeneity than the blood-derived protein.
通过一系列分析技术对在酿酒酵母中产生的重组人白蛋白和源自血液分级分离的人血清白蛋白进行了比较。这些结果表明这两种蛋白质在结构上是等同的。然而,在一些检测中观察到的差异表明,重组产品的结构异质性水平低于血液来源的蛋白质。