Kunimoto F, Arai K, Isa Y, Hasegawa Y, Fujita T
Intensive Care Unit, Gunma University School of Medicine, Maebashi.
Masui. 1996 Jan;45(1):21-6.
The Do2/VO2 balance of splanchnic organs after heart surgery was evaluated using two different methods; the measurement of hepato-splanchnic oxygen extraction ratio (OERspl) and gastric intramucosal pH (pHi) employing a hepatic venous catheter and a gastric tonometric catheter. Systemic oxygen extraction ratio was within normal ranges during the 24 hours of the experiment, but pHi decreased and OERspl increased significantly at 6 hours after admission to the ICU. Both pHi and OERspl returned gradually to normal levels after 24 hours. We conclude that a period of 24 hours is required to restore sufficient blood flow in the visceral organs to meet oxygen demand and that the pHi reflects the splanchnic DO2/VO2 balance as well as OERspl.
采用两种不同方法评估心脏手术后内脏器官的氧输送(Do2)/氧消耗(VO2)平衡;使用肝静脉导管和胃张力计导管测量肝内脏氧摄取率(OERspl)和胃黏膜内pH值(pHi)。在实验的24小时内,全身氧摄取率在正常范围内,但入住重症监护病房(ICU)6小时后,pHi降低,OERspl显著升高。24小时后,pHi和OERspl均逐渐恢复至正常水平。我们得出结论,需要24小时来恢复内脏器官足够的血流以满足氧需求,并且pHi与OERspl一样反映内脏Do2/VO2平衡。