Mizushima A, Sakai H, Hanzawa K, Horimoto Y, Kugimiya T
Department of Anesthesiology, Juntendo University School of Medicine, Tokyo.
Masui. 1996 Jan;45(1):86-90.
A 480 g, 38-day-old female infant underwent ventriculo-peritoneal shunt surgery for hydrocephalus after intra-ventricular hemorrhage. The patient was born at a gestational age of 25 weeks and 5 days, weighing 600 g, as one of twins by a cesarean section. Although respiratory distress syndrome developed, it was relieved with surfactant. The esophagus was easily perforated by a gastric tube. At the age of 7 days, PDA was closed conservatively with indomethacin. Anesthesia was induced and maintained with fentanyl (induction dose 4 micrograms.kg-1, total dose 6 micrograms.kg-1) and vecuronium. Ventilation was controlled with oxygen and air (FIO2 0.21-0.25). The main problems encountered by anesthetists in the perioperative period were; fluid management (hyperkalemia, hyponatremia, infusion volume), bradycardia due to increased intracranial pressure, body temperature control (hypothermia), and transport to the operating room. In anesthesia for extremely low birth weight (extremely premature) infants, utmost care and proficient procedure are required because of their immaturity, fragility and smallness.
一名480克、38日龄的女婴在脑室内出血后因脑积水接受了脑室-腹腔分流手术。该患者孕25周零5天出生,体重600克,为双胞胎之一,通过剖宫产出生。尽管出现了呼吸窘迫综合征,但使用表面活性剂后症状得到缓解。胃管很容易导致食管穿孔。7天时,动脉导管未闭通过吲哚美辛保守治疗闭合。麻醉诱导和维持使用芬太尼(诱导剂量4微克/千克,总剂量6微克/千克)和维库溴铵。通气使用氧气和空气控制(吸入氧浓度0.21 - 0.25)。麻醉医生在围手术期遇到的主要问题包括:液体管理(高钾血症、低钠血症、输液量)、颅内压升高导致的心动过缓、体温控制(体温过低)以及转运至手术室。对于极低出生体重(极早产儿)婴儿的麻醉,由于其不成熟、脆弱和体型小,需要格外小心和熟练的操作。