自体献血期间静脉补铁与口服补铁的比较

Intravenous vs. oral iron supplementation during autologous blood donation.

作者信息

Gesemann M, Mielsch I, Gentner P R, Weigand H, Scheiermann N

机构信息

Institut für Laboratoriumsmedizin, St. Markus-Krankenhaus, Frankfurt/M., Germany.

出版信息

Beitr Infusionsther Transfusionsmed. 1996;33:180-3.

PMID:8865945

Abstract

Prior to hip replacement surgery, 197 patients (123 women, 74 men, age 18-86 years) donated up to 4 units of blood once weekly if their hemoglobin concentrations exceeded 11.5 g/dl. They received an oral (200 mg iron sulfate daily) or intravenous (200 mg iron saccharate or 125 mg iron gluconate in 500 ml 0.9% NaCl weekly) iron replacement. Correlating the number of donated blood units with the form of iron substitution, no effect of i.v. iron was seen in men. Women who received i.v. iron substitution were able to donate 4 units of blood more often than with oral iron.

摘要

在进行髋关节置换手术前，197名患者（123名女性，74名男性，年龄18 - 86岁），如果血红蛋白浓度超过11.5 g/dl，每周献血最多4单位。他们接受口服（每日200毫克硫酸亚铁）或静脉注射（每周在500毫升0.9%氯化钠中注射200毫克蔗糖铁或125毫克葡萄糖酸铁）补铁治疗。将献血单位数与补铁形式相关联后发现，静脉注射铁剂对男性没有影响。接受静脉注射补铁治疗的女性比接受口服补铁的女性更频繁地能够捐献4单位血液。