[自体献血中的红细胞生成与铁代谢]
[Erythropoiesis and iron metabolism in autologous blood donation].
作者信息
Eckstein R, Emmler J, Fellmer F, Zeiler T, Zimmermann R, Zingsem J, Heuft H G, Kirgis A, Weisbach V
机构信息
Abteilung Innere Medizin und Poliklinik m.S. Hämatologie und Onkologie, Universitätsklinikum Rudolf Virchow, Freie Universität Berlin.
出版信息
Infusionsther Transfusionsmed. 1992 Apr;19(2):56-8.
Autologous blood donation before elective surgery has been widely endorsed as good transfusion practice. Although only 6 percent of patients undergoing elective orthopedic surgery are unable to donate 3 autologous units, 40 percent cannot donate 4 units because they become anemic [1,2]. According to the results of our study this must be due to different problems in bone marrow dynamics, which cannot be overcome by unselected use of human recombinant erythropoietin alone [3].
择期手术前的自体输血已被广泛认可为良好的输血实践。尽管接受择期骨科手术的患者中只有6%无法捐献3个自体单位的血液，但40%的患者无法捐献4个单位，因为他们出现了贫血[1,2]。根据我们的研究结果，这一定是由于骨髓动力学存在不同问题，仅无差别地使用重组人促红细胞生成素无法克服这些问题[3]。
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