Watson W J, Freeman J, O'Brien C, Benson M
Department of Perinatal Medicine, Sioux Valley Hospital, South Dakota, USA.
Am J Perinatol. 1996 Aug;13(6):371-2. doi: 10.1055/s-2007-994358.
A 28-year-old woman with a mechanical aortic heart valve experienced an embolic stroke in early pregnancy after her anticoagulation therapy was changed from warfarin to heparin. This occurred despite use of a subcutaneous heparin infusion pump and optimal anticoagulation. Thromboembolism can occur in pregnant patients with mechanical heart valves despite optimal heparin therapy.
一名28岁患有机械主动脉心脏瓣膜的女性，在抗凝治疗从华法林改为肝素后，于妊娠早期发生了栓塞性中风。尽管使用了皮下肝素输注泵并进行了最佳抗凝治疗，但仍发生了这种情况。尽管进行了最佳的肝素治疗，患有机械心脏瓣膜的孕妇仍可能发生血栓栓塞。
