García Páez J M, Carrera San Martin A, García Sestafe J V, Jorge Herrero E, Navidad R, Cordón A, Castillo-Olivares J L
Servicio de Cirugla Experimental, Clínica Puerta de Hierro, Madrid, Spain.
Biomaterials. 1996 Sep;17(17):1677-83. doi: 10.1016/0142-9612(96)87647-2.
The purpose of this study was to assess the elastic behaviour of calf pericardium used in the construction of cardiac bioprosthesis valve leaflets, sutured with different types of commercially available sutures: silk, Gore-Tex, Surgilene and nylon. Thirty-two samples (four series of eight samples each) were subjected to tensile strength testing to breakage. The breaking stress (MPa) ranged between 4.89 MPa for samples sutured with Gore-Tex and 5.22 MPa for those sewn with nylon. Three samples from each series were subjected to a stepwise stress test, involving increasing levels of stress followed by return to zero, to define the elastic limit (the cut-off point beyond which strain is no longer reversible). Analysis of the results provided the mathematical functions that govern the elastic behaviour (stress/strain) within the elastic range for each type of sutured sample. The series sutured with Surgilene presented the highest mean value (1.649 MPa). Finally, a statistical study was carried out to determine which series showed the greatest probability of having the least interaction between the thread and the pericardium. Allowing an interval of +/- 10%, Gore-Tex showed the best probability in this respect. However, real fatigue testing is necessary to definitively determine which is the best suture to use.
本研究的目的是评估用于构建心脏生物假体瓣膜小叶的小牛心包的弹性行为，这些心包用不同类型的市售缝线缝合：丝线、戈尔特斯（Gore-Tex）、 Surgilene和尼龙。三十二个样本（四个系列，每个系列八个样本）进行拉伸强度测试直至断裂。断裂应力（MPa）范围在使用戈尔特斯缝合的样本的4.89 MPa至使用尼龙缝合的样本的5.22 MPa之间。每个系列的三个样本进行逐步应力测试，包括增加应力水平然后回到零，以确定弹性极限（超过该点应变不再可逆的截止点）。结果分析提供了控制每种缝合样本弹性范围内弹性行为（应力/应变）的数学函数。用Surgilene缝合的系列呈现出最高平均值（1.649 MPa）。最后，进行了一项统计研究，以确定哪个系列在缝线与心包之间相互作用最小方面显示出最大的可能性。在允许±10%的区间内，戈尔特斯在这方面显示出最佳可能性。然而，需要进行实际疲劳测试才能最终确定哪种缝线是最佳选择。
