Della-Latta P
Clinical Microbiology Service, Columbia-Presbyterian Medical Center, New York, New York, USA.
Clin Lab Med. 1996 Sep;16(3):677-95.
The algorithm of the mycobacteriology laboratory of the 1990s relies heavily on growth-dependent procedures that are slow and labor intensive. The introduction of nucleic acid-based direct amplification tests portends future laboratories where molecular diagnostic assays will prevail. Financial constraints mandate an interdisciplinary approach to establish clinical pathways and rational tailoring of current protocols to curtail expensive overuse of dwindling resources.
20世纪90年代的分枝杆菌学实验室算法严重依赖于依赖生长的程序,这些程序既缓慢又耗费人力。基于核酸的直接扩增检测的引入预示着未来分子诊断检测将占主导地位的实验室格局。财务限制要求采用跨学科方法来建立临床路径,并合理调整当前方案,以减少对日益减少的资源的昂贵过度使用。