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作为阿尔茨海默病标志物的局部用托吡卡胺的瞳孔反应。

Pupillary response to topical tropicamide as a marker for Alzheimer's disease.

作者信息

Treloar A J, Assin M, Macdonald A J

机构信息

Division of Psychiatry, United Medical and Dental Schools (Guy's), Bexley Hospital, Kent, UK.

出版信息

Br J Clin Pharmacol. 1996 Mar;41(3):256-7. doi: 10.1111/j.1365-2125.1996.tb00194.x.

Abstract

The mydriatic response to eyedrops of the anticholinergic drug tropicamide at very low concentration (0.01%) was studied in subjects with Alzheimer's disease (AD, n = 10) and multi-infarct dementia (MID, n = 10). There was no significant difference in pupillary response between the two groups. The test is unlikely to be useful in differentiating different types of dementia.

摘要

在患有阿尔茨海默病(AD,n = 10)和多发梗死性痴呆(MID,n = 10)的受试者中,研究了极低浓度(0.01%)的抗胆碱能药物托吡卡胺滴眼液的散瞳反应。两组之间的瞳孔反应没有显著差异。该测试不太可能用于区分不同类型的痴呆。

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