Stipek S, Novak L, Crkovska J, Zima T, Platenik J
1st Department of Medical Chemistry and Biochemistry, Charles University, Praha, Czech Republic.
Sb Lek. 1994;95(4):289-95.
Primary biochemical role of xanthine oxidoreductase (XOR, EC 1.1.1.204 and EC 1.1.3.22.) is the hydroxylation of hypoxathine and xanthine to form uric acid. This enzyme may produce very reactive oxygen forms which can be pathogenic. Although it is one of the longest known and most continuously studied enzymes, its biological function remains unclear. The review of these aspects is discussed in relation to the authors' experimental results.
黄嘌呤氧化还原酶（XOR，EC 1.1.1.204和EC 1.1.3.22）的主要生化作用是将次黄嘌呤和黄嘌呤羟基化以形成尿酸。这种酶可能产生具有高反应活性的氧形式，而这些氧形式可能具有致病性。尽管它是已知时间最长且研究持续时间最长的酶之一，但其生物学功能仍不清楚。本文结合作者的实验结果对这些方面进行了综述。
