Desvaux B, Abraham P, Colin D, Leftheriotis G, Saumet J L
Laboratoire d'exploration vasculaire et de médecine du sport, C.H.U. d'Angers, France.
Clin Physiol. 1996 Jan;16(1):1-7. doi: 10.1111/j.1475-097x.1996.tb00551.x.
Ankle to arm index (AAI) defined as the ratio of ankle systolic blood pressure (ASBP), to brachial systolic blood pressure is largely used in the study of lower extremity arterial disease (LEAD). To study the hypothesis of the shunt of blood away from the skin as the explanation of AAI decrease in exercise, we studied the AAI and ASBP responses to an increase in cardiac output originating from an increase either in muscle blood flow (exercise) or in cutaneous blood flow (thermal stress). Brachial systolic pressure, ankle systolic pressure and heart rate (HR) were measured in 9 healthy subjects at rest, during heart thermal stress and following maximal exercise on a cycle ergometer. Compared to resting values, AAI decreased in all subjects from 1.05 +/- 0.07 to 0.75 +/- 0.07 (P < 0.05) 1 min following exercise and from 1.08 +/- 0.07 to 0.94 +/- 0.05 (P < 0.05) during heat stress. On the other hand, HR increased from 72.8 +/- 12.2 to 112.4 +/- 19.6 (P < 0.05) min following exercise and from 75.5 +/- 13.6 to 96.8 +/- 15.3 (P < 0.05) during heat stress. Since a comparable relation exists between AAI and HR in thermal stress and exercise, we suggest that the decrease in AAI in normal subjects following exercise is due to turbulences at high flow levels, rather than the shunting of blood to active muscles in exercise.
踝臂指数（AAI）定义为踝部收缩压（ASBP）与肱动脉收缩压之比，在下肢动脉疾病（LEAD）研究中被广泛应用。为了研究血液从皮肤分流作为运动时AAI降低原因的这一假说，我们研究了AAI和ASBP对因肌肉血流量增加（运动）或皮肤血流量增加（热应激）导致的心输出量增加的反应。对9名健康受试者在静息状态、热应激期间以及在自行车测力计上进行最大运动后，测量其肱动脉收缩压、踝部收缩压和心率（HR）。与静息值相比，所有受试者在运动后1分钟时AAI从1.05±0.07降至0.75±0.07（P<0.05），在热应激期间从1.08±0.07降至0.94±0.05（P<0.05）。另一方面，运动后1分钟时HR从72.8±12.2升至112.4±19.6（P<0.05），热应激期间从75.5±13.6升至96.8±15.3（P<0.05）。由于在热应激和运动中AAI与HR之间存在类似关系，我们认为正常受试者运动后AAI降低是由于高血流水平时的血流紊乱，而非运动时血液分流至活跃肌肉。
