Srisombut C, Rojanasakul A, Suchartwatnachai C, Choktanasiri W, Weerakiet S, Chinsomboon S
Department of Obstetrics and Gynecology, Mahidol University, Bangkok, Thailand.
J Med Assoc Thai. 1995 Dec;78(12):657-61.
As assisted reproductive technology is being developed, in vitro fertilization and embryo transfer (IVF-ET) are the treatments of choice for many infertility problems. The outcome of pregnancies achieved by IVF-ET is different from that of spontaneous pregnancies. In this retrospective study, the outcome of pregnancies from 400 IVF treatment cycles performed from October 1991 to October 1994 were reported. There were 80 pregnancies (20% per oocyte retrieval, 21.9% per embryo transfer) with an increased rate of abortion (30%), multiple pregnancy (20%), ectopic pregnancy (6.25%), heterotopic pregnancy (1.25%), preterm delivery (11.8%), low birth weight (35.8%) and cesarean section (62.7%). This study shows that the complication rate of pregnancies from IVF-ET cycles was higher than that found in spontaneous pregnancies. Some complications such as multiple pregnancies may be prevented by limiting the number of transferred embryos. From this study, all IVF-ET pregnancy should be considered as high risk pregnancies.
随着辅助生殖技术的发展，体外受精和胚胎移植（IVF-ET）是许多不孕症问题的首选治疗方法。IVF-ET所实现的妊娠结局与自然妊娠不同。在这项回顾性研究中，报告了1991年10月至1994年10月进行的400个IVF治疗周期的妊娠结局。共有80例妊娠（每个取卵周期为20%，每个胚胎移植周期为21.9%），流产率（30%）、多胎妊娠（20%）、异位妊娠（6.25%）、同期复孕（1.25%）、早产（11.8%）、低出生体重（35.8%）和剖宫产率（62.7%）均有所增加。本研究表明，IVF-ET周期妊娠的并发症发生率高于自然妊娠。一些并发症，如多胎妊娠，可以通过限制移植胚胎的数量来预防。从这项研究来看，所有IVF-ET妊娠都应被视为高危妊娠。
