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[孤立性毛细血管型血管母细胞瘤,细胞型。2例临床、影像学及解剖病理学研究]

[Solitary capillary hemangioblastoma, cellular variant. Clinical, radiological, and anatomo-pathological study of 2 cases].

作者信息

Del Basso De Caro M, De Stefano V, Bucciero A, Iaconetta G, Cappabianca P, Vizioli L, Maiuri F

机构信息

Istituto di Patologia, Università di Napoli, Federico II.

出版信息

Pathologica. 1995 Oct;87(5):518-21.

PMID:8868178
Abstract

Two cases of the rare cellular variant of the solitary capillary haemangioblastoma are reported. On MR study both tumors appeared as cerebellar contrast-enhancing masses, without evidence of intra- or perilesional blood vessels. Histologically, they showed compact groups of polygonal or rectangular cells separated by compressed small capillaries. There were no reticulin fibres among cell clusters. The stromal cells were found to be immunopositive for neuron-specific enolase (NSE), factor VIII-related antigen (von Wille-brand factor), Ulex europaeus lectin, and glial frillary acidic protein (GFAP). The findings are discussed in light of the pertinent literature.

摘要

报告了两例罕见的孤立性毛细血管型血管母细胞瘤细胞变体病例。在磁共振成像(MR)研究中,两个肿瘤均表现为小脑强化肿块,病灶内或病灶周围均无血管迹象。组织学上,它们显示为由受压小毛细血管分隔的紧密多边形或矩形细胞群。细胞簇之间没有网状纤维。发现基质细胞对神经元特异性烯醇化酶(NSE)、VIII因子相关抗原(血管性血友病因子)、欧洲荆豆凝集素和胶质纤维酸性蛋白(GFAP)呈免疫阳性。结合相关文献对这些发现进行了讨论。

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