[人正常免疫球蛋白制剂的抗毒素和抗菌活性评估。I. 肌内注射用免疫球蛋白（IMIG）和静脉注射用免疫球蛋白（IVIG）制剂中的破伤风抗毒素水平]
[Evaluation of antitoxin and antibacterial activity of human preparations of normal immunoglobulin. I. Level of tetanus antitoxin in preparations of IMIG and IVIG].
作者信息
Zakrzewska A, Rymkiewicz D
机构信息
Zakład Badania Surowic i Szczepionek Państwowego Zakładu Higieny w Warszawie.
出版信息
Przegl Epidemiol. 1995;49(4):381-4.
PMID:8868196
Abstract
The level of anti-tetanus antibodies were measured in 791 lots of IMIG and 330 lots of IVIG of human normal gamma globulin. The antibody levels varied 15-80 IU/ml of IMIG lots and 5-20 IU/ml of IVIG lots. Every lot of human normal gamma globulin (IMIG or IVIG) having high anti-tetanus activity may be an acceptable alternative to specific tetanus immune globulin.
摘要
检测了791批人正常丙种球蛋白肌肉注射用免疫球蛋白（IMIG）和330批静脉注射用免疫球蛋白（IVIG）中的抗破伤风抗体水平。IMIG批次的抗体水平在15 - 80 IU/ml之间，IVIG批次的抗体水平在5 - 20 IU/ml之间。每批具有高抗破伤风活性的人正常丙种球蛋白（IMIG或IVIG）都可能是特异性破伤风免疫球蛋白的可接受替代物。
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