[环孢素A局部应用治疗坏疽性脓皮病取得成功]

[Successful topical administration of cyclosporin A in pyoderma gangraenosum].

作者信息

Theissen U, Luger T A, Schwarz T

机构信息

Hautklinik, Westfälischen Wilhelms-Universität, Münster.

出版信息

Hautarzt. 1996 Feb;47(2):132-5. doi: 10.1007/s001050050390.

DOI:10.1007/s001050050390

PMID:8868458

Abstract

Therapy of pyoderma gangrenosum can be complicated by side effects of the various systemic therapies, including corticosteroids, azathioprin and cyclosporin A. In this paper we report on a 49-year-old patient presenting with recalcitrant pyoderma gangrenosum who was treated successfully by topical application of cyclosporin A. Cyclosporin A serum levels were always in the subtherapeutic range, and no side effects were observed.

摘要

坏疽性脓皮病的治疗可能会因各种全身治疗的副作用而变得复杂，这些治疗包括皮质类固醇、硫唑嘌呤和环孢素A。在本文中，我们报告了一名49岁患有顽固性坏疽性脓皮病的患者，他通过局部应用环孢素A成功治愈。环孢素A的血清水平始终处于亚治疗范围，且未观察到副作用。