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p70核糖体蛋白S6激酶：一个具有多种变体的谜团。

p70 S6 kinase: an enigma with variations.

作者信息

Proud C G

机构信息

Department of Biosciences, University of Kent at Canterbury, UK.

出版信息

Trends Biochem Sci. 1996 May;21(5):181-5.

PMID:8871403
Abstract

The S6 ribosomal protein is phosphorylated by p70 S6 kinase (p70S6k). Although the cellular role of S6 phosphorylation is still not fully clear, studies on p70S6k and its activation have revealed the existence of a novel signalling pathway, clues to the mechanism of action of certain immunosuppressants and insights into the control of gene expression at the levels of transcription and translation.

摘要

S6核糖体蛋白被p70 S6激酶（p70S6k）磷酸化。尽管S6磷酸化在细胞中的作用仍不完全清楚，但对p70S6k及其激活的研究揭示了一种新的信号通路的存在、某些免疫抑制剂作用机制的线索以及在转录和翻译水平上对基因表达调控的见解。

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