Gibbins I L, Matthew S E, Bridgman N, Morris J L
Department of Anatomy and Histology, School of Medicine, Flinders University of South Australia, Adelaide, Australia.
Neurosci Lett. 1996 Aug 9;213(3):197-200. doi: 10.1016/0304-3940(96)12885-8.
We have used a combination of retrograde axonal tracing and intracellular dye injections to determine the soma size of sympathetic vasoconstrictor neurons projecting from the superior cervical ganglion to the cutaneous vascular bed of the eartips, or to the vascular beds of the masseter muscle, of guinea-pigs. Neurons projecting to vasculature of the masseter muscle had a cross-sectional area of 956 +/- 295 microns2 (mean +/- SD; n = 45 cells) and were significantly larger than neurons projecting to the vasculature of the eartip skin (mean cross-sectional area +/- SD, 604 +/- 251 microns2; n = 39 cells). These results are consistent with physiological observations showing that muscle vasoconstrictor neurons have faster conduction velocities than cutaneous vasoconstrictor neurons. Furthermore, they suggest that muscle vasoconstrictor neurons may innervate a larger volume of vasculature compared with cutaneous vasoconstrictor neurons.
我们采用逆行轴突追踪和细胞内染料注射相结合的方法，来确定豚鼠从颈上神经节投射到耳尖皮肤血管床或咬肌血管床的交感缩血管神经元的胞体大小。投射到咬肌血管的神经元的横截面积为956±295平方微米（平均值±标准差；n = 45个细胞），明显大于投射到耳尖皮肤血管的神经元（平均横截面积±标准差，604±251平方微米；n = 39个细胞）。这些结果与生理学观察结果一致，即肌肉缩血管神经元的传导速度比皮肤缩血管神经元更快。此外，这些结果还表明，与皮肤缩血管神经元相比，肌肉缩血管神经元可能支配更大体积的血管。
