Thornton S K, Withington D J, McCrossan D, Ingham N J
Department of Physiology, University of Leeds, UK.
Neurosci Lett. 1996 Aug 9;213(3):216-20. doi: 10.1016/0304-3940(96)12851-2.
Extracellular multi-unit responses to visual stimuli were recorded in the cells of the superficial layers of the superior colliculus (SC) in four groups of adult guinea-pigs: a control group, a strobe-reared group, a dark-reared group and a group with the ipsilateral visual cortex removed acutely. Single unit visual responses were also recorded in a control and a dark-reared group. When guinea-pigs were either strobe or dark-reared from birth, the number of directionally selective responses in the superficial SC decreased significantly. Acute removal of the visual cortex had no affect on the number of directionally selective cells recorded in the SC. The correlation between azimuthal visual receptive field and rostrocaudal position of the recording electrode in the SC was not significantly different from the control group following strobe, dark-rearing or acute visual cortex removal. These data imply that, during early development, visual information is necessary for directional selectivity of the visual responses in the superficial SC. However, the map of visual azimuthal space is essentially unperturbed by visual restriction (in the form of dark or strobe-rearing) or acute visual cortex removal.
在四组成年豚鼠的上丘（SC）浅层细胞中记录了对视觉刺激的细胞外多单位反应：一个对照组、一个频闪饲养组、一个暗饲养组和一个急性切除同侧视觉皮层的组。还在一个对照组和一个暗饲养组中记录了单细胞视觉反应。当豚鼠从出生起就进行频闪或暗饲养时，浅层SC中方向选择性反应的数量显著减少。急性切除视觉皮层对SC中记录的方向选择性细胞数量没有影响。在频闪、暗饲养或急性切除视觉皮层后，SC中方位视觉感受野与记录电极的 rostrocaudal 位置之间的相关性与对照组没有显著差异。这些数据表明，在早期发育过程中，视觉信息对于浅层SC中视觉反应的方向选择性是必要的。然而，视觉方位空间图谱基本上不受视觉限制（以暗饲养或频闪饲养的形式）或急性切除视觉皮层的影响。
