Ogata N, Jochum W, Aguzzi A, Fournier J Y, Yonekawa Y
Department of Neurosurgery, University Hospital of Zürich, Switzerland.
Surg Neurol. 1996 Nov;46(5):477-80. doi: 10.1016/s0090-3019(96)00222-4.
Primary intracranial squamous cell carcinomas are extremely rare, and commonly manifest as malignant transformations of intracranial epidermoid cysts.
A case of primary squamous cell carcinoma invading the ventral brain stem and the trigeminal entry zone is described. The tumor was microsurgically totally removed via a paramedian supracerebellar approach. Three years after the operation the tumor recurred, and was again totally removed using the same approach.
The patient showed no postoperative neurologic deterioration except for a transient deterioration of gait disturbances. The pathologic diagnosis was a recurrence of the squamous cell carcinoma.
Since primary intracranial squamous cell carcinomas grow slowly and have a well demarcated capsule, total removal should be considered whenever possible.
原发性颅内鳞状细胞癌极为罕见，通常表现为颅内表皮样囊肿的恶性转化。
描述了1例侵犯脑桥腹侧和三叉神经入区的原发性鳞状细胞癌病例。通过小脑上经中旁入路对肿瘤进行显微手术全切除。术后3年肿瘤复发，再次采用相同入路将肿瘤全切除。
除步态障碍短暂恶化外，患者术后无神经功能恶化。病理诊断为鳞状细胞癌复发。
由于原发性颅内鳞状细胞癌生长缓慢且有边界清晰的包膜，应尽可能考虑全切除。
