el-Gamel A, Bridgewater B, Doran H, Yonan N A, Campbell C S, Hooper T L
Department of Cardiothoracic Surgery, Wythenshawe Hospital, Manchester, UK.
Eur J Cardiothorac Surg. 1996;10(8):702-4. doi: 10.1016/s1010-7940(96)80390-3.
Granulomatous involvement of the myocardium is a rapidly fatal disease of uncertain aetiology rarely diagnosed premorbidly. We report a patient who presented with mitral valve incompetence and congestive cardiac failure who underwent a successful mitral valve repair but could not be weaned from cardiopulmonary bypass. Urgent heart transplantation was successfully performed and histological studies of the explanted heart revealed granulomatous myocarditis involving the mitral subvalvular apparatus. Endomyocardial biopsy may be necessary in young patients presenting with mitral valve disease of unknown aetiology.
心肌肉芽肿累及是一种病因不明、迅速致命的疾病，很少在发病前得到诊断。我们报告一例患者，该患者表现为二尖瓣关闭不全和充血性心力衰竭，成功接受了二尖瓣修复术，但无法脱离体外循环。紧急心脏移植手术成功实施，切除心脏的组织学研究显示肉芽肿性心肌炎累及二尖瓣瓣下结构。对于病因不明的二尖瓣疾病的年轻患者，心内膜活检可能是必要的。
