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白塞病:约旦患者的临床研究。

Behçet's disease: clinical study of Jordanian patients.

作者信息

al-Aboosi M M, al Salem M, Saadeh A, al-Jamal M, Hijawi M, Khammash M, Sharma R V

机构信息

Department of Dermatology, Jordan University of Science and Technology, School of Medicine, Irbid, Jordan.

出版信息

Int J Dermatol. 1996 Sep;35(9):623-5. doi: 10.1111/j.1365-4362.1996.tb03685.x.

DOI:10.1111/j.1365-4362.1996.tb03685.x
PMID:8876287
Abstract

BACKGROUND

Behçet's disease is a chronic, recurrent, inflammatory disorder characterized by the triad of oral and genital ulcers and ocular lesions. The etiology is unknown. This is the first report giving details of the clinical manifestations of Behçet's disease in Jordanian patients.

METHODS

Twenty patients with Behçet's disease were studied to determine the clinical pattern in the North of Jordan. The patients were seen in Princess Basma Teaching Hospital in North Jordan. They presented to various clinics and underwent full clinical examination. Data for each patient on all features of Behçet's disease were recorded on a standard form. A comparison was made between Behçet's disease in Jordan and other countries in the region.

RESULTS

Of the 20 patients, 14 were men and six women, giving a ratio of 2.3:1. Their ages ranged from 14 to 58 years. All had mouth ulcers, 65% genital ulcers, 65% ocular involvement, 55% joint involvement, 35% skin lesions, 20% vascular lesions, and 5% gastrointestinal involvement. The oral ulcers were the first manifestation of the disease process in 70% of our patients. Skin lesions, genital ulcers, and involvement of the central nervous system and the pulmonary system were less frequent in our study.

CONCLUSIONS

Although it is difficult to obtain figures as to the incidence and prevalence of Behçet's disease in Jordan, the clinical manifestations, with a few exceptions, are similar to those in other countries in the region.

摘要

背景

白塞病是一种慢性、复发性炎症性疾病,其特征为口腔溃疡、生殖器溃疡和眼部病变三联征。病因不明。这是首篇详细报道约旦患者白塞病临床表现的报告。

方法

对20例白塞病患者进行研究,以确定约旦北部的临床模式。这些患者在约旦北部的巴斯玛公主教学医院就诊。他们前往不同科室并接受了全面的临床检查。每位患者白塞病所有特征的数据都记录在标准表格上。对约旦的白塞病与该地区其他国家的情况进行了比较。

结果

20例患者中,男性14例,女性6例,男女比例为2.3:1。他们的年龄在14至58岁之间。所有患者均有口腔溃疡,65%有生殖器溃疡,65%有眼部受累,55%有关节受累,35%有皮肤病变,20%有血管病变,5%有胃肠道受累。在我们的患者中,70%的口腔溃疡是疾病过程的首发表现。在我们的研究中,皮肤病变、生殖器溃疡以及中枢神经系统和肺部系统受累的情况较少见。

结论

尽管很难获得约旦白塞病发病率和患病率的数据,但除少数例外,其临床表现与该地区其他国家相似。

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