Prystowsky E N
St. Vincent Hospital, Indianapolis, Indiana, USA.
Control Clin Trials. 1996 Jun;17(3 Suppl):28S-36S. doi: 10.1016/s0197-2456(96)00042-6.
This paper reviews the Electrophysiologic Study versus Holter Monitoring (ESVEM) trial, addressing several areas of concern including potential enrollment bias, an inadequate electrophysiologic testing protocol during drug therapy, and an unexpectedly high recurrence rate in patients deemed to be controlled by either method. The paper concludes that there are insufficient data to warrant extrapolation of the ESVEM results to survivors of cardiac arrest.
本文回顾了电生理研究与动态心电图监测(ESVEM)试验,探讨了几个令人关注的领域,包括潜在的入选偏倚、药物治疗期间电生理测试方案不充分,以及在被认为通过两种方法之一得到控制的患者中意外出现的高复发率。本文得出结论,没有足够的数据来保证将ESVEM结果外推至心脏骤停幸存者。