Pérez S, Mouhous-Riou N, Nifant'ev N E, Tsvetkov Y E, Bachet B, Imberty A
Ingeniérie Moléculaire, Institut National de la Recherche Agronomique, Nantes, France.
Glycobiology. 1996 Jul;6(5):537-42. doi: 10.1093/glycob/6.5.537.
This work describes the first crystal structure ever reported of a histo-blood group carbohydrate antigen: Le(x). This study provides a detailed description of the conformation of two crystallographic independent molecules in a highly hydrated environment along with their hydrogen bonding properties and packing features. Some interactions observed between adjacent trisaccharides can provide the basis for involvement of Le(x)-Le(x) interactions in cell-cell adhesion.
这项研究描述了首次报道的组织血型碳水化合物抗原——Le(x)的晶体结构。本研究详细描述了在高度水合环境中两个晶体学独立分子的构象，以及它们的氢键性质和堆积特征。在相邻三糖之间观察到的一些相互作用可以为Le(x)-Le(x)相互作用参与细胞间黏附提供基础。
