Dreger P, Glass B, Uharek L, Schmitz N
Second Department of Medicine and Bone Marrow Transplantation Unit, University of Kiel, Germany.
J Hematother. 1996 Aug;5(4):331-7. doi: 10.1089/scd.1.1996.5.331.
Increasing use is being made of mobilized peripheral blood as a source of hematopoietic stem and progenitor cells for transplantation. Initially, these efforts were focused on autologous applications. However, many centers are now using cells derived from normal donors mobilized with recombinant hematopoietic growth factors for allogeneic transplantation. This article reviews the key issues associated with the use of these cells for hematologic reconstitution and summarizes important recent developments in the field.
越来越多地使用动员的外周血作为造血干细胞和祖细胞移植的来源。最初，这些努力主要集中在自体应用上。然而，现在许多中心正在使用由重组造血生长因子动员的正常供体来源的细胞进行异基因移植。本文综述了与使用这些细胞进行血液重建相关的关键问题，并总结了该领域最近的重要进展。
