高效液相色谱法测定苯氧乙醇、对羟基苯甲酸甲酯、对羟基苯甲酸乙酯、对羟基苯甲酸丙酯、对羟基苯甲酸异丁酯、对羟基苯甲酸丁酯和克霉唑盐酸盐。
High performance liquid chromatographic determination of phenoxetol, methyl paraben, ethyl paraben, n-propyl paraben, iso-butyl paraben, n-butyl paraben and croconazole.HCl.
作者信息
Akhtar M J, Khan S, Roy I M, Jafri I A
机构信息
Research and Development Laboratories, Wellcome Pakistan Limited, Karachi, Pakistan.
出版信息
J Pharm Biomed Anal. 1996 Aug;14(11):1609-13. doi: 10.1016/0731-7085(96)01777-3.
A high performance liquid chromatographic technique has been used to determine phenoxetol, methyl paraben, ethyl paraben, n-propyl paraben, iso-butyl paraben, n-butyl paraben and croconazole.HCl. The method developed involves isocratic, reversed phase chromatography. The range of quantitation was found to be 90-135.0 micrograms ml-1 for phenoxetol, 2.0-30.0 micrograms ml-1 for methyl paraben, 0.5-7.5 micrograms ml-1 for ethyl paraben, 0.3-4.5 micrograms ml-1 for n-propyl paraben, 0.3-4.5 micrograms ml-1 for iso-butyl paraben, 0.5-7.5 micrograms ml-1 for n-butyl paraben and 20.0-300 micrograms ml-1 for croconazole.HCl. Linear regression analysis of the data demonstrates the adequate performance of the method in terms of precision and accuracy.
一种高效液相色谱技术已被用于测定苯氧乙醇、对羟基苯甲酸甲酯、对羟基苯甲酸乙酯、对羟基苯甲酸正丙酯、对羟基苯甲酸异丁酯、对羟基苯甲酸正丁酯和克霉唑盐酸盐。所开发的方法涉及等度反相色谱法。发现苯氧乙醇的定量范围为90 - 135.0微克/毫升，对羟基苯甲酸甲酯为2.0 - 30.0微克/毫升，对羟基苯甲酸乙酯为0.5 - 7.5微克/毫升，对羟基苯甲酸正丙酯为0.3 - 4.5微克/毫升，对羟基苯甲酸异丁酯为0.3 - 4.5微克/毫升，对羟基苯甲酸正丁酯为0.5 - 7.5微克/毫升，克霉唑盐酸盐为20.0 - 300微克/毫升。数据的线性回归分析表明该方法在精密度和准确度方面表现良好。
Zotero 插件