Carreon L Y, Ito T, Yamada M, Uchiyama S, Takahashi H, Ikuta F
Department of Orthopaedic Surgery, Niigata University School of Medicine, Japan.
J Spinal Disord. 1996 Aug;9(4):313-6.
We examined the histologic changes in the disc in two cases of traumatic cervical disc herniation and compared it with previous histologic studies done in degenerative disc herniations. Differences in the absorption of herniated cartilage endplate and annulus fibrosus are also discussed. The herniated disc material was surrounded by fibrovascular tissue. Vessels in this fibrovascular tissue were seen to continue into the annulus fibrosus but not into the endplate. Scattered cartilage fragments and macrophages in the fibrovascular tissue were localized around the margin of the disc. The herniation produced a visible defect in the injured intervertebral disc. On serial sections, the amount of herniated annulus fibrosus appeared to be smaller than the defect produced in the annulus fibrosus of the injured disc. However, the herniated endplate seemed to be the same size as the defect produced in the endplate of the injured disc. Fibrovascular tissue formation, vessel infiltration into annulus fibrosus, and the presence of peripheral macrophages suggest marginal absorption. The cartilage fragments are probably remnants of disc tissue produced during the process of absorption. These findings are similar to that seen in degenerated herniated discs and suggest an absorptive process. Absorption of the annulus is more significant than absorption of the endplate.
我们检查了2例创伤性颈椎间盘突出症椎间盘的组织学变化，并将其与先前对退变椎间盘突出症所做的组织学研究进行了比较。还讨论了突出的软骨终板和纤维环吸收情况的差异。突出的椎间盘组织被纤维血管组织包绕。可见该纤维血管组织中的血管延伸至纤维环，但未延伸至终板。纤维血管组织中的散在软骨碎片和巨噬细胞位于椎间盘边缘周围。突出在受伤的椎间盘中造成了明显的缺损。在连续切片上，突出的纤维环量似乎小于受伤椎间盘纤维环产生的缺损。然而，突出的终板似乎与受伤椎间盘终板产生的缺损大小相同。纤维血管组织形成、血管浸润至纤维环以及外周巨噬细胞的存在提示边缘吸收。软骨碎片可能是吸收过程中产生的椎间盘组织残余。这些发现与退变椎间盘突出症中所见相似，提示存在吸收过程。纤维环的吸收比终板的吸收更显著。
