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Effect of CI-988, a cholecystokinin-B receptor antagonist, on lactate-induced panic.

作者信息

Cowley D S, Adams J B, Pyke R E, Cook J, Zaccharias P, Wingerson D, Roy-Byrne P P

机构信息

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, USA.

出版信息

Biol Psychiatry. 1996 Sep 15;40(6):550-2. doi: 10.1016/0006-3223(96)00163-1.

DOI:10.1016/0006-3223(96)00163-1
PMID:8879478
Abstract
摘要

相似文献

1
Effect of CI-988, a cholecystokinin-B receptor antagonist, on lactate-induced panic.
Biol Psychiatry. 1996 Sep 15;40(6):550-2. doi: 10.1016/0006-3223(96)00163-1.
2
Single-site findings in a study of the safety and efficacy of a CCKB receptor antagonist, CI-988, in the treatment of generalized anxiety disorder.
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The cholecystokinin-B receptor antagonist CI-988 failed to affect CCK-4 induced symptoms in panic disorder patients.
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Effect of CI-988 on cholecystokinin tetrapeptide-induced panic symptoms in healthy volunteers.CI-988对健康志愿者中胆囊收缩素四肽诱导的惊恐症状的影响。
Biol Psychiatry. 1995 Dec 1;38(11):742-6. doi: 10.1016/0006-3223(95)00081-X.
5
[Suppression of conditioned fear by administration of CCKB receptor antagonist PD135158].[通过给予CCKB受体拮抗剂PD135158抑制条件性恐惧]
Nihon Shinkei Seishin Yakurigaku Zasshi. 1998 Feb;18(1):15-8.
6
A double-blind, placebo-controlled study of a CCK-B receptor antagonist, CI-988, in patients with generalized anxiety disorder.一项关于胆囊收缩素B受体拮抗剂CI-988治疗广泛性焦虑症患者的双盲、安慰剂对照研究。
J Clin Psychopharmacol. 1995 Dec;15(6):428-34. doi: 10.1097/00004714-199512000-00007.
7
Placebo-controlled trial of the CCK-B antagonist, CI-988, in panic disorder.
Biol Psychiatry. 1999 Sep 15;46(6):860-2. doi: 10.1016/s0006-3223(99)00090-6.
8
Effect of the cholecystokinin-B receptor antagonist L-365,260 on lactate-induced panic attacks in panic disorder patients.
Biol Psychiatry. 1996 Oct 15;40(8):804-6. doi: 10.1016/0006-3223(96)00250-8.
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Suppression of conditioned fear by administration of CCKB receptor antagonist PD135158.
Neuropeptides. 1999 Dec;33(6):483-6. doi: 10.1054/npep.1999.0766.
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Neurochemical actions of CCK underlying the therapeutic potential of CCK-B antagonists.CCK-B拮抗剂治疗潜力背后CCK的神经化学作用。
Neuropeptides. 1991 Jul;19 Suppl:85-9. doi: 10.1016/0143-4179(91)90087-y.

引用本文的文献

1
Cholecystokinin and psychiatric disorders : role in aetiology and potential of receptor antagonists in therapy.胆囊收缩素与精神障碍：在发病机制中的作用及受体拮抗剂的治疗潜力。
CNS Drugs. 1997 Aug;8(2):134-52. doi: 10.2165/00023210-199708020-00005.
2
Elevated cholecystokininergic tone constitutes an important molecular/neuronal mechanism for the expression of anxiety in the mouse.胆囊收缩素能张力升高是小鼠焦虑表达的重要分子/神经元机制。
Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3881-6. doi: 10.1073/pnas.0505407103. Epub 2006 Feb 28.