Lapham G, Aranko K, Hanhijärvi H, Humphreys D M
Boehringer Ingelheim Limited, Bracknell, Berkshire.
Br J Hosp Med. 1996;56(5):231-3.
Sodium clodronate is effective in the management of osteolytic lesions, hypercalcaemia and bone pain associated with skeletal metastasis. Clinical and biochemical data underpin a licensed total daily dose of 1600-3200 mg.
氯膦酸钠在治疗与骨转移相关的溶骨性病变、高钙血症和骨痛方面有效。临床和生化数据支持每日许可总剂量为1600 - 3200毫克。