Scadden D T
Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Hematol Oncol Clin North Am. 1996 Oct;10(5):1149-61. doi: 10.1016/s0889-8588(05)70390-7.
During the course of HIV disease a broad spectrum of hematologic disorders develop including abnormalities in blood cell generation, survival, and function Alterations in coagulation parameters may evolve associated with disruption of immunoglobulin or factor production. This article reviews the manifestations and pathophysiology of these abnormalities and discusses the role for growth factor support.
在HIV疾病过程中,会出现广泛的血液系统疾病,包括血细胞生成、存活和功能异常。凝血参数的改变可能会随着免疫球蛋白或因子产生的破坏而演变。本文综述了这些异常的表现和病理生理学,并讨论了生长因子支持的作用。