Kaufman J H, Douglass H O, Blake W, Moore R, Rao U N
Surg Gynecol Obstet. 1977 Sep;145(3):357-63.
The effect of initial presenting symptoms, degree of tumor differentiation and type of surgical procedure on survival was evaluated in a 20 year review of 42 patients with chondrosarcoma. Therapy of patients presenting initially with a painless mass resulted in a median survival period longer than 13 years versus less than three years of the initial symptom was pain. Median survival time of patients with well differentiated chondrosarcomas was more than ten years compared with 1.2 years if the tumor was less well differentiated. Even if the sarcoma was nonresectable, these factors influenced the survival time. Since chondrosarcomas tended to recur locally rather than to metastasize, a number of patients who had a recurrence after the initial surgical excision could be saved by a more radical secondary operation.
在一项对42例软骨肉瘤患者进行的20年回顾性研究中，评估了初始症状、肿瘤分化程度和手术方式对生存的影响。最初表现为无痛性肿块的患者接受治疗后的中位生存期超过13年，而初始症状为疼痛的患者中位生存期不到3年。高分化软骨肉瘤患者的中位生存时间超过10年，而肿瘤分化程度较低的患者为1.2年。即使肉瘤不可切除，这些因素也会影响生存时间。由于软骨肉瘤倾向于局部复发而非转移，许多在初次手术切除后复发的患者可以通过更彻底的二次手术挽救。
