Tsuji M H, Horigome H, Yamashita M
Department of Anaesthesiology, Mitsui Memorial Hospital, Tokyo, Japan.
Paediatr Anaesth. 1996;6(5):405-9. doi: 10.1046/j.1460-9592.1996.d01-11.x.
We studied the haemodynamic and cardiovascular effects of epidural anaesthesia with plain bupivacaine 0.75 ml.kg-1 in 13 unpremedicated ASA 1 children using measurements of heart rate, blood pressure and M-mode echocardiography. Under general anaesthesia, M-mode echocardiographic evaluation of left ventricular function in each patient was performed at four points (after general anaesthesia, point A; 5 min, 10 min and 25 min after epidural anaesthesia, point B; point C; and point D, respectively). Results were compared between point A and B, A and C, A and D, B and C, B and D, C and D. HR decreased significantly at 10 min (point C) and 25 min (point D) and MBP decreased at 5 min (point B) and 10 min (point D) compared to point A. No other M-mode cardiographic indices were changed at any point. Epidural anaesthesia using 0.25% bupivacaine 0.75 ml.kg-1 did not affect LV function in young children.
我们对13例未用术前药的美国麻醉医师协会（ASA）分级为1级的儿童，使用心率、血压测量及M型超声心动图，研究了0.75 ml.kg-1普通布比卡因硬膜外麻醉的血流动力学和心血管效应。在全身麻醉下，对每位患者左心室功能进行M型超声心动图评估，共4个时间点（全身麻醉后，A点；硬膜外麻醉后5分钟、10分钟和25分钟，分别为B点、C点和D点）。比较A与B、A与C、A与D、B与C、B与D、C与D各点的结果。与A点相比，10分钟（C点）和25分钟（D点）时心率显著降低，5分钟（B点）和10分钟（D点）时平均动脉压降低。其他任何时间点M型心动图指标均无变化。使用0.25%布比卡因0.75 ml.kg-1进行硬膜外麻醉对幼儿左心室功能无影响。
