Poles L, Theodor E
Medical Dept. E, Beilinson Medical Center, Petah Tikva.
Harefuah. 1996 Jun 16;130(12):817-9, 879.
Drug-induced meningitis is rarely included in the differential diagnosis of aseptic (usually recurrent) meningitis. A 74-year-old man who suffered from recurrent aseptic meningitis following re-exposures to trimethoprim-sulphamethoxazole (Resprim) is presented. The clinical and laboratory findings resembled those found in bacterial meningitis, excluding normal glycorrachia. Extensive microbiological, serologic and imaging studies did not disclose any relevant findings. All symptoms and signs resolved rapidly following drug withdrawal, and findings on follow-up lumbar puncture were normal.
药物性脑膜炎很少被纳入无菌性（通常为复发性）脑膜炎的鉴别诊断中。本文报告了一名74岁男性，他在再次接触甲氧苄啶-磺胺甲恶唑（复方新诺明）后出现复发性无菌性脑膜炎。临床和实验室检查结果与细菌性脑膜炎相似，但脑脊液糖含量正常。广泛的微生物学、血清学和影像学检查均未发现任何相关结果。停药后所有症状和体征迅速缓解，后续腰椎穿刺检查结果正常。
