Clercx C, Wallon J, Gilbert S, Snaps F, Coignoul F
Small Animal Clinic, Faculty of Veterinary Medicine, University of Liège, Sart Tilman, Belgium.
J Small Anim Pract. 1996 Sep;37(9):423-7. doi: 10.1111/j.1748-5827.1996.tb02441.x.
Fifty-four dogs with nasal tumours were included in this study. Based on histopathology 52 tumours were malignant (36 epithelial and 16 mesenchymal) and two were benign (one oncocytoma and one pleiomorphic adenoma). Malignancy was significantly more frequently diagnosed by imprint cytology (81 per cent of the cases) than by brush cytology (56 per cent). Brush cytology was a significantly more sensitive technique in epithelial than in mesenchymal tumours, while the sensitivity of imprint cytology was not affected by the histological type. Brush cytology determined an epithelial origin in 88 per cent of epithelial tumours, and imprint cytology in 90 per cent. In mesenchymal tumours, the scores were significantly lower, the histological type being determined in only 20 per cent and 50 per cent, using brush and imprint cytology, respectively.
本研究纳入了54只患有鼻肿瘤的犬。根据组织病理学,52个肿瘤为恶性(36个上皮性和16个间叶性),2个为良性(1个嗜酸性细胞瘤和1个多形性腺瘤)。印片细胞学诊断恶性肿瘤的频率(81%的病例)显著高于刷片细胞学(56%)。刷片细胞学在上皮性肿瘤中比在间叶性肿瘤中是一种显著更敏感的技术,而印片细胞学的敏感性不受组织学类型的影响。刷片细胞学在88%的上皮性肿瘤中确定了上皮起源,印片细胞学在90%的上皮性肿瘤中确定了上皮起源。在间叶性肿瘤中,得分显著更低,使用刷片和印片细胞学分别仅在20%和50%的病例中确定了组织学类型。