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肠内喂养导致的食管粪石

Esophageal bezoar resulting from enteral feedings.

作者信息

Cremer S A, Gelfand D W

机构信息

Department of Radiology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27157-1088, USA.

出版信息

JPEN J Parenter Enteral Nutr. 1996 Sep-Oct;20(5):371-3. doi: 10.1177/0148607196020005371.

Abstract

Esophageal bezoars are rare but are known to occur in patients with structural or functional abnormalities of the esophagus. Additionally, sucralfate and casein containing enteral feeding formulas have been implicated in the formation of esophageal bezoars, particularly in the setting of decreased esophageal pH. We present a case in which a patient with functional impairment of the esophagus related to myasthenia gravis developed an esophageal bezoar. Gastroesophageal reflux, altered esophageal pH, and direct instillation of feeding formula through a rent in the feeding tube were additional factors likely leading to bezoar formation in this patient. Endoscopic examination revealed puttylike material consistent with coagulated enteral feeding formula. An esophagram demonstrated a large bezoar filling the middle and distal thirds of the esophagus. The conditions predisposing to bezoar formation and the proposed mechanisms are discussed. We also summarize the reported cases of esophageal bezoars related to enteral feeding formula, sucralfate, or both.

摘要

食管粪石较为罕见,但已知在食管存在结构或功能异常的患者中会出现。此外,含硫糖铝和酪蛋白的肠内营养配方奶与食管粪石的形成有关,尤其是在食管pH值降低的情况下。我们报告一例与重症肌无力相关的食管功能障碍患者发生食管粪石的病例。胃食管反流、食管pH值改变以及通过饲管破损处直接注入营养配方奶是该患者可能导致粪石形成的其他因素。内镜检查发现呈油灰样物质,与凝固的肠内营养配方奶相符。食管造影显示一个大粪石占据食管中下段。本文讨论了易导致粪石形成的情况及可能的机制。我们还总结了与肠内营养配方奶、硫糖铝或两者相关的食管粪石的报道病例。

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