Caliari S, Vantini I, Sembenini C, Gregori B, Carnielli V, Benini L
Division of Gastroenterologic Rehabilitation, University of Verona, Italy.
Scand J Gastroenterol. 1996 Sep;31(9):863-7. doi: 10.3109/00365529609051993.
It has been suggested that some of the limitations of the Van de Kamer method for fecal fat measurement could be overcome with the Jeejeebhoy method or the near-infrared reflectance assay.
To test this hypothesis, a fecal fat test was carried out with the three methods, adding butter or MCT oil to the diet of four steatorrhoic patients. An in vitro recovery study of long- and medium-chain triglycerides was also performed.
The Jeejeebhoy method measured long- and medium-chain fats more accurately than the Van de Kamer method. It found consistently higher steatorrhea values. Mean results of the near-infrared reflectance analysis resembled those of the Van de Kamer method, but with wide discordance of individual data.
The Jeejeebhoy method is more accurate than the Van de Kamer method for fecal fat measurement. The difference may be clinically relevant when most fecal fatty acids derive from medium-chain triglycerides. Near-infrared reflectance may be a viable proposition only when a greater degree of approximation is acceptable.
有人提出,粪便脂肪测量的范德卡默方法的一些局限性可以通过杰吉博伊方法或近红外反射测定法来克服。
为了验证这一假设,对四名脂肪泻患者的饮食中添加黄油或中链甘油三酯,并用这三种方法进行粪便脂肪检测。还进行了长链和中链甘油三酯的体外回收率研究。
杰吉博伊方法比范德卡默方法更准确地测量长链和中链脂肪。它发现脂肪泻值一直较高。近红外反射分析的平均结果与范德卡默方法的结果相似,但个体数据差异较大。
在粪便脂肪测量方面,杰吉博伊方法比范德卡默方法更准确。当大多数粪便脂肪酸来自中链甘油三酯时,这种差异可能具有临床意义。只有在可以接受更大程度的近似值时,近红外反射法才可能是一个可行的方法。