Strauer B E, Kandolf R, Mall G, Maisch B, Mertens T, Schwartzkopff B, Schultheiss H P
Medical Clinic and Policlinic B, University of Düsseldorf, Germany.
Acta Cardiol. 1996;51(4):347-71.
On the basis of several, partially divergent definitions, myocarditis-unlike the often aetiologically unexplained (idiopathic) cardiomyopathies (dilated, hypertrophic, restrictive)-can be classified as c specific disease of the myocardium. This disease often has a known cause and can be due to a large variety of aetiological agents (viral, autoreactive, toxic, infectious processes, etc.) (1). A question still to be answered is whether there is a connection between dilated cardiomyopathy and myocarditis, i.e. whether (virus-induced) myocarditis can progress via a subacute or chronic stage to dilated cardiomyopathy. This question is of considerable diagnostic and therapeutic relevance. The following consensus report thus deals with the clinically important problems related to the diagnosis of myocarditis and dilated cardiomyopathy, examines the aetiological role of immunological mechanisms and discusses the treatment of the two diseases and prognostic factors.
基于多种部分存在差异的定义,与通常病因不明(特发性)的心肌病(扩张型、肥厚型、限制型)不同,心肌炎可被归类为心肌的一种特定疾病。这种疾病通常有已知病因,可能由多种致病因素引起(病毒、自身免疫、毒性、感染过程等)(1)。一个仍有待回答的问题是扩张型心肌病与心肌炎之间是否存在关联,即(病毒诱导的)心肌炎是否会经由亚急性或慢性阶段发展为扩张型心肌病。这个问题具有相当大的诊断和治疗意义。因此,以下共识报告探讨了与心肌炎和扩张型心肌病诊断相关的临床重要问题,研究了免疫机制的病因学作用,并讨论了这两种疾病的治疗及预后因素。