Tsujimoto M, Sawaki M, Mikasa K, Konishi M, Hamada K, Maeda K, Sakamoto M, Teramoto S, Mori K, Narita N, Kita E, Masutani T, Sano R
Second Department of Internal Medicine, Nara Medical University.
Kansenshogaku Zasshi. 1996 Aug;70(8):808-14. doi: 10.11150/kansenshogakuzasshi1970.70.808.
We performed a clinical study of 26 cases (27 episodes) of acute respiratory infection with H. influenzae by trans tracheal aspiration (TTA) from May 1987 to April 1995. 15 episodes (14 cases) were bronchitis and 12 episodes (12 cases) were pneumonia. 8 episodes were monomicrobial infection and 19 episodes were polymicrobial infection. Compared to the group of patients of monomicrobial infection, the number of elderly patients and the levels of WBC and CRP were higher in the group of patients of monomicroibal infection. In bronchitis cases, monomicrobial infections of H. influenzae were 7 episodes and polymicrobial infection containing H. influenzae were 8 episodes. In the latter group, PaO2 level was lower and CRP was higher on average. All patients recovered, but the period for treatment was longer in the latter group. In the pneumonia group, only one episode was monomicrobal infection and 11 episodes were polymicrobial infection. Inspite of treatment, one patient died. It was considered that polymicrobial infection was an important factor of acute respiratory infection with H. influenzae.
1987年5月至1995年4月，我们通过经气管抽吸（TTA）对26例（27次发作）流感嗜血杆菌引起的急性呼吸道感染进行了临床研究。15次发作（14例）为支气管炎，12次发作（12例）为肺炎。8次发作是单一微生物感染，19次发作是多微生物感染。与单一微生物感染患者组相比，多微生物感染患者组中老年患者数量以及白细胞和CRP水平更高。在支气管炎病例中，流感嗜血杆菌单一微生物感染7次发作，含流感嗜血杆菌的多微生物感染8次发作。在后一组中，平均PaO2水平较低而CRP较高。所有患者均康复，但后一组的治疗时间更长。在肺炎组中，仅1次发作是单一微生物感染，11次发作是多微生物感染。尽管进行了治疗，仍有1例患者死亡。多微生物感染被认为是流感嗜血杆菌引起的急性呼吸道感染的一个重要因素。
