Russell B G, Russell M B, Praetorius F, Russell C A
Copenhagen County Dental Clinic for Handicapped, Gentofte, Denmark.
Clin Genet. 1996 Jul;50(1):36-40. doi: 10.1111/j.1399-0004.1996.tb02343.x.
Shed deciduous teeth from patients with tuberous sclerosis, cerebral palsy, Down syndrome, phenylketonuria and healthy persons were examined with a surface microscope. We found enamel pits in all 87 deciduous teeth from the 20 patients with tuberous sclerosis, but in none of the 253 deciduous teeth from 142 controls constituting patients with cerebral palsy, phenylketonuria and Down syndrome as well as healthy persons. Enamel pits always occurred in the facial surface of the central incisor, lateral incisor and canine, while the number of enamel pits in the other surfaces of the deciduous teeth varied from none to nine. Ground sections examined microscopically revealed an undisturbed pattern of incremental lines (Retzius striae) surrounding the pits. In five dental sacs from patients with tuberous sclerosis, microscopic examination showed that the inner surface of the operculum was remarkably more irregular than in control patients.
用表面显微镜检查了结节性硬化症、脑瘫、唐氏综合征、苯丙酮尿症患者以及健康人的脱落乳牙。我们在20例结节性硬化症患者的全部87颗乳牙中发现了釉质凹坑，但在142名对照者（包括脑瘫、苯丙酮尿症、唐氏综合征患者以及健康人）的253颗乳牙中均未发现。釉质凹坑总是出现在中切牙、侧切牙和尖牙的唇面，而乳牙其他表面的釉质凹坑数量从无到九个不等。显微镜检查磨片显示，凹坑周围的生长线（芮氏线）模式未受干扰。在5例结节性硬化症患者的牙囊中，显微镜检查显示，与对照患者相比，龈盖的内表面明显更不规则。
