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本文引用的文献

1
Studies on transformations of Hemophilus influenzae. I. Competence.流感嗜血杆菌转化的研究。I. 感受态。
J Gen Physiol. 1961 Jul;44(6):1201-27. doi: 10.1085/jgp.44.6.1201.
2
Regulation of competence development and sugar utilization in Haemophilus influenzae Rd by a phosphoenolpyruvate:fructose phosphotransferase system.磷酸烯醇丙酮酸：果糖磷酸转移酶系统对流感嗜血杆菌Rd感受态发育和糖利用的调控
Mol Microbiol. 1996 Sep;21(5):941-52. doi: 10.1046/j.1365-2958.1996.441420.x.
3
Characterization of the Haemophilus influenzae topA locus: DNA topoisomerase I is required for genetic competence.流感嗜血杆菌topA基因座的特征：遗传转化能力需要DNA拓扑异构酶I 。
Gene. 1996 Feb 22;169(1):25-31. doi: 10.1016/0378-1119(95)00777-6.
4
Dual response regulators (NarL and NarP) interact with dual sensors (NarX and NarQ) to control nitrate- and nitrite-regulated gene expression in Escherichia coli K-12.双响应调节因子（NarL和NarP）与双传感器（NarX和NarQ）相互作用，以控制大肠杆菌K-12中硝酸盐和亚硝酸盐调节的基因表达。
J Bacteriol. 1993 Jun;175(11):3259-68. doi: 10.1128/jb.175.11.3259-3268.1993.
5
Gene regulation by phosphate in enteric bacteria.肠道细菌中磷酸盐对基因的调控
J Cell Biochem. 1993 Jan;51(1):47-54. doi: 10.1002/jcb.240510110.
6
Novel members of the two-component signal transduction genes in Escherichia coli.大肠杆菌中双组分信号转导基因的新成员。
J Biochem. 1993 Sep;114(3):350-7. doi: 10.1093/oxfordjournals.jbchem.a124180.
7
Phosphoenolpyruvate:carbohydrate phosphotransferase systems of bacteria.细菌的磷酸烯醇丙酮酸：碳水化合物磷酸转移酶系统
Microbiol Rev. 1993 Sep;57(3):543-94. doi: 10.1128/mr.57.3.543-594.1993.
8
The Haemophilus influenzae adenylate cyclase gene: cloning, sequence, and essential role in competence.流感嗜血杆菌腺苷酸环化酶基因：克隆、序列及在感受态中的重要作用。
J Bacteriol. 1993 Nov;175(22):7142-9. doi: 10.1128/jb.175.22.7142-7149.1993.
9
The Haemophilus influenzae sxy-1 mutation is in a newly identified gene essential for competence.流感嗜血杆菌sxy - 1突变存在于一个新发现的对感受态至关重要的基因中。
J Bacteriol. 1994 Nov;176(22):6789-94. doi: 10.1128/jb.176.22.6789-6794.1994.
10
The Cpx two-component signal transduction pathway of Escherichia coli regulates transcription of the gene specifying the stress-inducible periplasmic protease, DegP.大肠杆菌的Cpx双组分信号转导途径调控着指定应激诱导周质蛋白酶DegP的基因的转录。
Genes Dev. 1995 Feb 15;9(4):387-98. doi: 10.1101/gad.9.4.387.

双组分信号转导系统和磷酸烯醇式丙酮酸：碳水化合物磷酸转移酶系统在流感嗜血杆菌Rd感受态发育中的作用

Role of the two-component signal transduction and the phosphoenolpyruvate: carbohydrate phosphotransferase systems in competence development of Haemophilus influenzae Rd.

作者信息

Gwinn M L, Yi D, Smith H O, Tomb J F

机构信息

Department of Molecular Biology and Genetics, Johns Hopkins University, School of Medicine, Baltimore, Maryland 21205, USA.

出版信息

J Bacteriol. 1996 Nov;178(21):6366-8. doi: 10.1128/jb.178.21.6366-6368.1996.

DOI:10.1128/jb.178.21.6366-6368.1996
PMID:8892843
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC178514/
Abstract

Haemophilus influenzae Rd becomes competent for transformation by nutritional downshift or transient anaerobic growth through a process that requires cyclic AMP receptor protein and adenylate cyclase. Insertion mutations in crr or ptsI of the phosphoenolpyruvate:carbohydrate phosphotransferase system lowered transformation frequencies, and the effect was reversed by the addition of cyclic AMP. However, insertions into H. influenzae homologs of two-component signal transduction genes had no effect on competence.

摘要

流感嗜血杆菌Rd通过营养物质降档或短暂厌氧生长，经一个需要环磷酸腺苷受体蛋白和腺苷酸环化酶的过程而具备转化能力。磷酸烯醇式丙酮酸：碳水化合物磷酸转移酶系统的crr或ptsI中的插入突变降低了转化频率，添加环磷酸腺苷可逆转此效应。然而，插入到双组分信号转导基因的流感嗜血杆菌同源物中对感受态没有影响。