Ruggieri M, Pavone V, Tiné A, Polizzi A, Magro G, Duray P H, Merino M, Albanese V
Division of Pediatric Neurology, University of Catania, Italy.
J Neurosurg. 1996 Nov;85(5):941-4. doi: 10.3171/jns.1996.85.5.0941.
Ossifying fibroma is a rare, benign, primary bone tumor that occurs most commonly in the mandible; a cranial vault location is extremely rare. In this report a case of symptomatic frontoparietotemporal ossifying fibroma with intracranial growth and cerebral displacement in a 12-year-old boy with neurofibromatosis type 1 (NF1) is described. Once excised the lesion did not recur. The skeletal system is frequently affected in NF1, and bone abnormalities are present in 50% to 70% of patients with this condition. The etiology of such lesions in NF1 is still controversial. To the authors' knowledge, ossifying fibromas of calvarial bones have not been described in NF1.
骨化性纤维瘤是一种罕见的良性原发性骨肿瘤，最常见于下颌骨；颅骨穹窿部位极为罕见。本报告描述了一名患有1型神经纤维瘤病（NF1）的12岁男孩，其额颞顶骨骨化性纤维瘤出现症状性颅内生长并导致脑移位。病变切除后未复发。NF1常累及骨骼系统，50%至70%的该疾病患者存在骨骼异常。NF1中此类病变的病因仍存在争议。据作者所知，NF1患者中尚未有颅骨骨化性纤维瘤的相关描述。
