Takaya M, Moritake K, Nagai H, Tsutsumi A, Yamasaki T
Department of Neurosurgery, Shimane Medical University.
Noshuyo Byori. 1993;10(1):87-90.
A rare case of ossifying cementicular fibroma of the left orbitofrontal bone that developed in a 12-year-old boy is presented. A hard, painless mass that was incidentally noticed gradually enlarged over 2 years. Skull X-rays showed a well-demarcated lesion with mixed sclerotic and osteolytic radiolucent changes in the left orbitofrontal bone. Computed tomography revealed an expansile intradiploic multilocular mass that was separated by bony trabeculae. T1-weighted magnetic resonance imaging demonstrated a multi-cystic iso-intense mass with homogeneous contrast enhancement. Left external carotid angiograms revealed a vague tumor stain that was mainly fed by the middle meningeal artery. Systemic bone scintigrams revealed a single abnormal uptake in the lesion. The skull tumor was totally removed. Histological examination demonstrated two different characteristic findings that were composed of fibrous dysplasia and cementifying fibroma, although most of the tumor appeared to be a highly cementicular form of fibro-osseous lesion. The pathological diagnosis was a cementicular variant of fibrous dysplasia.
本文报告了一例发生于一名12岁男孩左眶额骨的骨化性牙骨质纤维瘤罕见病例。一个偶然发现的硬的、无痛性肿块在2年时间里逐渐增大。颅骨X线显示左眶额骨有一个边界清晰的病变，伴有混合性硬化和骨质溶解的透光性改变。计算机断层扫描显示一个膨胀性的板障内多房肿块，被骨小梁分隔。T1加权磁共振成像显示一个多囊性等信号肿块，有均匀的对比增强。左颈外动脉血管造影显示一个模糊的肿瘤染色，主要由脑膜中动脉供血。全身骨闪烁扫描显示病变处有单一的异常摄取。颅骨肿瘤被完全切除。组织学检查显示出两种不同的特征性表现，由纤维发育异常和牙骨质化纤维瘤组成，尽管大多数肿瘤似乎是一种高度牙骨质化形式的纤维-骨病变。病理诊断为纤维发育异常的牙骨质化变体。
