Leffall L D, Chung E B, Dewitty R L, Cornwell E E, Blakey T M
Ann Surg. 1977 Sep;186(3):324-33. doi: 10.1097/00000658-197709000-00010.
We have presented our experience with 19 black patients who had familial polyposis coli, seven of whom had associated cancer. Four of the seven had multiple cancers. Seventeen of the 19 patients were female but most of the patients at risk in our series were female. Sixteen of the 19 had extracolonic manifestations which have been described as part of Gardner's syndrome. Although our series was quite small, larger series do not report as high an incidence of extracolonic manifestations. Follow-up was too short to make any statements concerning the development of cancer in the retained rectal stump.
我们介绍了19例患有家族性结肠息肉病的黑人患者的情况，其中7例伴有癌症。7例中有4例患有多发性癌症。19例患者中有17例为女性，但在我们的系列研究中，大多数有患病风险的患者是女性。19例中有16例有结肠外表现，这些表现被描述为加德纳综合征的一部分。尽管我们的系列研究规模很小，但更大规模的系列研究并未报告如此高的结肠外表现发生率。随访时间过短，无法就保留的直肠残端发生癌症的情况发表任何声明。
