吗啡-6-葡萄糖醛酸苷及其他相关阿片类药物在正辛醇、氯仿和丙二醇二壬酸酯-水体系中的分配 - Suppr

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Octanol-, chloroform-, and propylene glycol dipelargonat-water partitioning of morphine-6-glucuronide and other related opiates.

作者信息

Avdeef A, Barrett D A, Shaw P N, Knaggs R D, Davis S S

机构信息

Sirius Analytical Instruments Ltd., Riverside, East Sussex, U.K.

出版信息

J Med Chem. 1996 Oct 25;39(22):4377-81. doi: 10.1021/jm960073m.

DOI:10.1021/jm960073m

PMID:8893832

Abstract

摘要

相似文献

Octanol-, chloroform-, and propylene glycol dipelargonat-water partitioning of morphine-6-glucuronide and other related opiates.

J Med Chem. 1996 Oct 25;39(22):4377-81. doi: 10.1021/jm960073m.

Evaluating hydrogen-bond donor strength.

J Pharm Sci. 2000 Dec;89(12):1567-78. doi: 10.1002/1520-6017(200012)89:12<1567::aid-jps7>3.0.co;2-7.

[COMPARATIVE STUDY OF VARIOUS ELECTRODE SYSTEMS IN NON-AQUEOUS SOLVENTS: II. POTENTIOMETRIC DETERMINATIONS IN ACETIC ACID, CHLOROFORM, ACETONITRILE AND ACETONE].

Ann Pharm Fr. 1964 Apr;22:307-12.

Influence of chain length on oil-water ion-pair partitioning behavior of p-alkylpyridinium chlorides.

J Pharm Sci. 1972 Oct;61(10):1648-50. doi: 10.1002/jps.2600611027.

Association of deoxycholic acid in organic solvents.

J Pharm Sci. 1982 Aug;71(8):881-3. doi: 10.1002/jps.2600710810.

[Structure-activity relationship of synthetic and semisynthetic opioid agonists and antagonists].

Acta Pharm Hung. 1993 Nov;63(6):335-49.

A review of the chemical features associated with strong morphine-like activity.

Br J Anaesth. 1962 Apr;34:260-8. doi: 10.1093/bja/34.4.260.

[Ion-pair formation of phenyl alkylammonium salts in n-octanol and n-octanol-water mixtures].

Pharmazie. 1974 Jun;29(6):393-5.

Lipophilicity of morphine microspecies and their contribution to the lipophilicity profile.

Eur J Pharm Sci. 2012 Jan 23;45(1-2):205-10. doi: 10.1016/j.ejps.2011.11.007. Epub 2011 Nov 18.

[Acid-base titrimetry in non-aqueous solvents. Applications to drug analysis].

J Pharm Belg. 1968 Nov-Dec;23(11):527-86.

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Octanol-, chloroform-, and propylene glycol dipelargonat-water partitioning of morphine-6-glucuronide and other related opiates.

作者信息

Avdeef A, Barrett D A, Shaw P N, Knaggs R D, Davis S S

机构信息

Sirius Analytical Instruments Ltd., Riverside, East Sussex, U.K.

出版信息

J Med Chem. 1996 Oct 25;39(22):4377-81. doi: 10.1021/jm960073m.

DOI:10.1021/jm960073m

PMID:8893832

Abstract

摘要

相似文献

Octanol-, chloroform-, and propylene glycol dipelargonat-water partitioning of morphine-6-glucuronide and other related opiates.

J Med Chem. 1996 Oct 25;39(22):4377-81. doi: 10.1021/jm960073m.

Evaluating hydrogen-bond donor strength.

J Pharm Sci. 2000 Dec;89(12):1567-78. doi: 10.1002/1520-6017(200012)89:12<1567::aid-jps7>3.0.co;2-7.

[COMPARATIVE STUDY OF VARIOUS ELECTRODE SYSTEMS IN NON-AQUEOUS SOLVENTS: II. POTENTIOMETRIC DETERMINATIONS IN ACETIC ACID, CHLOROFORM, ACETONITRILE AND ACETONE].

Ann Pharm Fr. 1964 Apr;22:307-12.

Influence of chain length on oil-water ion-pair partitioning behavior of p-alkylpyridinium chlorides.

J Pharm Sci. 1972 Oct;61(10):1648-50. doi: 10.1002/jps.2600611027.

Association of deoxycholic acid in organic solvents.

J Pharm Sci. 1982 Aug;71(8):881-3. doi: 10.1002/jps.2600710810.

[Structure-activity relationship of synthetic and semisynthetic opioid agonists and antagonists].

Acta Pharm Hung. 1993 Nov;63(6):335-49.

A review of the chemical features associated with strong morphine-like activity.

Br J Anaesth. 1962 Apr;34:260-8. doi: 10.1093/bja/34.4.260.

[Ion-pair formation of phenyl alkylammonium salts in n-octanol and n-octanol-water mixtures].

Pharmazie. 1974 Jun;29(6):393-5.

Lipophilicity of morphine microspecies and their contribution to the lipophilicity profile.

Eur J Pharm Sci. 2012 Jan 23;45(1-2):205-10. doi: 10.1016/j.ejps.2011.11.007. Epub 2011 Nov 18.

[Acid-base titrimetry in non-aqueous solvents. Applications to drug analysis].

J Pharm Belg. 1968 Nov-Dec;23(11):527-86.

引用本文的文献

Buprenorphine Facilitates Rapid Weaning From Very-High-Dose Intrathecal Hydromorphone.

Cureus. 2024 Apr 27;16(4):e59134. doi: 10.7759/cureus.59134. eCollection 2024 Apr.

Development and Verification of a Full Physiologically Based Pharmacokinetic Model for Sublingual Buprenorphine in Healthy Adult Volunteers that Accounts for Nonlinear Bioavailability.

Drug Metab Dispos. 2024 Jul 16;52(8):785-796. doi: 10.1124/dmd.124.001643.

Forecasting Fetal Buprenorphine Exposure through Maternal-Fetal Physiologically Based Pharmacokinetic Modeling.

Pharmaceutics. 2024 Mar 8;16(3):375. doi: 10.3390/pharmaceutics16030375.

Pharmacological Treatments and Therapeutic Drug Monitoring in Patients with Chronic Pain.

Pharmaceutics. 2023 Aug 5;15(8):2088. doi: 10.3390/pharmaceutics15082088.

Heroin and its metabolites: relevance to heroin use disorder.

Transl Psychiatry. 2023 Apr 8;13(1):120. doi: 10.1038/s41398-023-02406-5.

A method of diamorphine (heroin) administration for harm reduction.

Harm Reduct J. 2023 Mar 30;20(1):44. doi: 10.1186/s12954-023-00758-1.

Predicting the efficacy of opioid sequestration by intravenous lipid emulsion using biologically relevant in vitro models of drug distribution.

Sci Rep. 2022 Nov 4;12(1):18683. doi: 10.1038/s41598-022-21790-4.

Physiologically-Based Pharmacokinetic Modeling to Investigate the Effect of Maturation on Buprenorphine Pharmacokinetics in Newborns with Neonatal Opioid Withdrawal Syndrome.

Clin Pharmacol Ther. 2022 Feb;111(2):496-508. doi: 10.1002/cpt.2458. Epub 2021 Nov 21.

In Silico Simulation of the Systemic Drug Exposure Following the Topical Application of Opioid Analgesics in Patients with Cutaneous Lesions.

Pharmaceutics. 2021 Feb 21;13(2):284. doi: 10.3390/pharmaceutics13020284.

Physiologically-Based Pharmacokinetic Model of Morphine and Morphine-3-Glucuronide in Nonalcoholic Steatohepatitis.

Clin Pharmacol Ther. 2021 Mar;109(3):676-687. doi: 10.1002/cpt.2037. Epub 2020 Nov 6.