Rahman M A, Jayson M I, Black C M
Department of Rheumatology, Royal Free Hospital, London, UK.
J Rheumatol. 1996 Oct;23(10):1816-7.
We describe 5 patients in whom the onset of systemic sclerosis followed shortly after episodes of trauma. The HLA-DR52 allele was common to all these patients. This raises the possibility that trauma may be associated with the onset of the disease in predisposed individuals. If this is the case, it seems likely that it may have advanced the development of the disease rather than being fundamentally responsible for it.
我们描述了5例患者，他们在创伤事件后不久便出现了系统性硬化症。所有这些患者都有HLA - DR52等位基因。这增加了创伤可能与易感个体的疾病发作相关的可能性。如果是这样的话，似乎它可能促进了疾病的发展，而不是该病的根本病因。
