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嗜酸性粒细胞增多性肌痛综合征:起病后2至4年的患者状况

Eosinophilia-myalgia syndrome: patient status 2-4 years after onset.

作者信息

Pincus T

机构信息

Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

出版信息

J Rheumatol Suppl. 1996 Oct;46:19-24; discussion 24-5.

PMID:8895178
Abstract

The clinical status of patients with the eosinophilia-myalgia syndrome (EMS) was studied 2-4 years after its description in 2 databases: (1) a structured review of 205 patients with EMS completed by 15 physicians 18-24 months after onset, which included symptoms, physical findings, laboratory data, and responses to treatments; (2) a self-report questionnaire completed by 344 patients with EMS 42-48 months after onset. Most patients continued to experience symptoms, but almost none experienced new signs of acute inflammation more than one year after onset of EMS. These databases, while presenting information concerning longterm outcomes of more patients with EMS than other reported sources, remain limited by patient selection and the absence of information concerning clinical symptoms before development of EMS.

摘要

在嗜酸性粒细胞增多性肌痛综合征(EMS)被描述后的2至4年,通过两个数据库对患者的临床状况进行了研究:(1)由15名医生在发病后18至24个月完成的对205例EMS患者的结构化回顾,内容包括症状、体格检查结果、实验室数据以及对治疗的反应;(2)344例EMS患者在发病后42至48个月完成的一份自我报告问卷。大多数患者仍有症状,但在EMS发病一年后,几乎没有人出现新的急性炎症体征。这些数据库虽然提供了比其他报告来源更多的EMS患者长期预后信息,但仍受患者选择的限制,且缺乏EMS发病前临床症状的相关信息。

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1
Eosinophilia-myalgia syndrome: patient status 2-4 years after onset.嗜酸性粒细胞增多性肌痛综合征:起病后2至4年的患者状况
J Rheumatol Suppl. 1996 Oct;46:19-24; discussion 24-5.
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The eosinophilia-myalgia syndrome: status of 205 patients and results of treatment 2 years after onset.嗜酸性粒细胞增多性肌痛综合征:205例患者发病2年后的状况及治疗结果
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Diagnostic bias in clinical decision making: an example of L-tryptophan and the diagnosis of eosinophilia-myalgia syndrome.临床决策中的诊断偏倚:以L-色氨酸与嗜酸性粒细胞增多性肌痛综合征的诊断为例
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引用本文的文献

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Immunogenetic risk and protective factors for the development of L-tryptophan-associated eosinophilia-myalgia syndrome and associated symptoms.L-色氨酸相关嗜酸性粒细胞增多性肌痛综合征及相关症状发生的免疫遗传风险和保护因素。
Arthritis Rheum. 2009 Oct 15;61(10):1305-11. doi: 10.1002/art.24460.